Volume 56 (2010) No. 3

Review Article

Epigenetic Studies in Human Diseases

(epigenetics / human diseases / methylation / histone acetylation / miRNA / cancer)

J. HALUŠKOVA

P. J. Šafarik University in Košice, Faculty of Medicine, Department of Medical Biology, Košice, Slovak Republic.

Pages: 83 - 96 (PDF)

Corresponding author: Jana Haluškova, P. J. Šafarik University in Košice, Faculty of Medicine, Department of Medical Biology, Trieda SNP 1, 040 66 Košice, Slovak Republic. e-mail: jana.haluskova(zavinac)upjs.sk

Received April 27, 2009. Accepted November 3, 2009.


Original Article

Saccharomyces cerevisiae Nuclear and Nucleolar Antigen Preservation for Immunoelectron Microscopy

(Saccharomyces cerevisiae / nucleolus / nucleus / chemical fixation / high-pressure freezing / freeze-substitution / immunoelectron microscopy)

V. MISTRIKOVA1, J. BEDNAR1,2

1Charles University in Prague, First Faculty of Medicine, Institute of Cellular Biology and Pathology, and Institute of Physiology, Academy of Sciences of the Czech Republic, Department of Cell Biology,Prague, Czech Republic
2CNRS/UJF, Laboratoire de Spectrometrie Physique, UMR 5588, BP87, St. Martin d’Heres, France

Pages: 97 - 109 (PDF)

Corresponding author: Veronika Mistrikova, Charles University in Prague, First Faculty of Medicine, Institute of Cellular Biology and Pathology, Albertov 4, 128 01 Prague 2, Czech Republic. Phone: (+420) 224 968 010; e-mail: vmist(zavinac)lf1.cuni.cz

Received October 27, 2009. Accepted January 26, 2010.


Original Article

Insights into the Role of IL-12B and IFN-γ Cytokine Gene Polymorphisms in HIV-1/AIDS Infection

(IL-12B / IFN-γ / pro-inflammatory / cytokine / polymorphism / RFLP / ARMS / HIV-1/AIDS)

R. C. SOBTI1, A. M. SALIH1, B. NEGA1, A. H. SEYED2, K. RUPINDER1, K. VIJESH2, W. AJAY2

1Department of Biotechnology, Panjab University, Chandigarh, India
2Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh,India

Pages: 110 - 115 (PDF)

Corresponding author: Ranbir Chander Sobti, Department of Biotechnology, Panjab University, 160014-Chandigarh, India. Phone: 0172-2534085; Fax:.0172-25341022; e-mail: rcsobti(zavinac)pu.ac.in

Received July 1, 2009. Accepted November 25, 2009.


Original Article

Role of the PPARα Leu162Val and PPARγ2 Pro12Ala Gene Polymorphisms in Weight Change after 2.5-Year Follow-up in Czech Obese Women

(PPARγ2 / Pro12Ala polymorphism / obesity / PPARα / Leu162Val polymorphism / body mass index changes / psycho-behavioural factors and genetics)

B. ALDHOON1,2, H. ZAMRAZILOVA2, I. ALDHOON HAINEROVA3, P. ŠRAMKOVA2,4, J. SPALOVA2, M. KUNEŠOVA2, B. BENDLOVA2, V. HAINER2

1Department of Cardiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
2Institute of Endocrinology, Prague, Czech Republic
3Charles University in Prague, Third Faculty of Medicine, Department of Pediatrics and Center for Research of Diabetes, Metabolism and Nutrition, Prague, Czech Republic
4Obesity Management Unit of the Clinical Centre ISCARE I.V.F., Prague, Czech Republic

Pages: 116 - 123 (PDF)

Corresponding author: Bashar Aldhoon, Department of Cardiology, Institute for Clinical and Experimental Medicine, Videňska 1958/9, 140 21 Prague 4, Czech Republic. Phone: (+420) 236 055 006; Fax: (+420) 261 362 985; e-mail: aldhoon(zavinac)gmail.com

Received: August 30, 2009. Accepted January 11, 2010.


Original Article

Effect of Diplacone on LPS-Induced Inflammatory Gene Expression in Macrophages

(geranyl flavanone / inflammation / MCP-1 / mRNA / TNF-α / ZFP36)

J. HOŠEK1, V. ZAVALOVA2, K. ŠMEJKAL1, M. BARTOŠ1,3

1Department of Natural Drugs, 2Department of Human Toxicology and Pharmacology, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic
3Genex CZ, Brno, Czech Republic

Pages: 124 - 130 (PDF)

Corresponding author: Jan Hošek, Department of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1-3, 612 42 Brno, Czech Republic. Phone: (+420) 541 562 839; e-mail: hosekj(zavinac)vfu.cz

Received September 14, 2009. Accepted November 5, 2009.


Short Communication

INSIG2 Promoter Variant, Obesity Markers and Lipid Parameters – No Association in a Large Slavonic Caucasian Population Sample

(INSIG / BMI / polymorphism)

J. A. HUBAČEK1,2,3, L. KUTHANOVA1, R. BOHUSLAVOVA1,2, V. ADAMKOVA1,3, V. LANSKA1, T. MEITINGER4, A. PFEUFER4

1Institute for Clinical and Experimental Medicine, Department of Experimental Medicine, Prague, Czech Republic
2Centre for Cardiovascular Research, Prague, Czech Republic
3University of South Bohemia in Česke Budějovice, Faculty of Public Health and Social Studies, Ceske Budejovice, Czech Republic
4Institute of Human Genetics, Helmholtz Centrum Munchen, Munich, Germany

Pages: 131 - 134 (PDF)

Corresponding author: Jaroslav A. Hubaček, IKEM-DEM-LMG, Videňska 1958/9, 140 21 Prague 4, Czech Republic. Phone: (+420) 261 363 367; Fax: (+420) 241 721 666; e-mail: jahb(zavinac)ikem.cz

Received August 10, 2009. Accepted November 11, 2009.