Volume 59 (2013) No. 1

Review Article

Availability of Haematopoietic Niches for Transplanted Stem Cells

(mouse / haematopoiesis / haematopoietic stem cell / progenitors / niche / bone marrow transplantation / irradiation / cytostatics / engraftment / stem cell mutations)

K. Forgáčová, E. Nečas

Centre of Experimental Haematology and Institute of Pathological Physiology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic

Pages: 1 - 14 (PDF)

Corresponding author: Katarína Forgáčová, Institute of Pathological Physiology, First Faculty of Medicine, Charles University in Prague, U Nemocnice 5, 128 53 Prague 2, Czech Republic. Phone: (+420) 224 965 913; Fax: (+420) 224 912 834; e-mail: kforg@lf1.cuni.cz

Received July 2, 2012. Accepted July 9, 2012.

Review Article

Proteinuria and Hypertension in Patients Treated with Inhibitors of the VEGF Signalling Pathway – Incidence, Mechanisms and Management

(VEGF inhibition / proteinuria / hypertension / bevacizumab / sunitinib / sorafenib)

P. Tesařová1, V. Tesař2

1Department of Oncology, 2Department of Nephrology, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic

Pages: 15 - 25 (PDF)

Corresponding author: Petra Tesařová, Department of Oncology, First Faculty of Medicine, Charles University in Prague and General University Hospital, Karlovo náměstí 32, 120 00 Prague 2, Czech Republic. e-mail: tesarova.petra@seznam.cz

Received August 21, 2012. Accepted September 19, 2012.

Original article

In Vivo Growth of Mantle Cell Lymphoma Xenografts in Immunodeficient Mice Is Positively Regulated by VEGF and Associated with Significant Up-regulation of CD31/PECAM1

(mantle cell lymphoma / angiogenesis / CD31 / VEGF)

J. Molinský1,2, M. Klánová1,2, B. Maswabi1, T. Soukup3, M. Trněný2,4, E. Nečas1, J. Živný1, P. Klener1,2

1Institute of Pathological Physiology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic

21st Department of Medicine – Department of Haematology, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic

3Department of Histology and Embryology, Medical Faculty in Hradec Králové, Charles University in Prague, Hradec Králové, Czech Republic

4Institute of Haematology and Blood Transfusion, Prague, Czech Republic

Pages: 26 - 31 (PDF)

Corresponding author: Jan Molinsky, Institute of Pathological Physiology, First Faculty of Medicine, Charles University in Prague, U Nemocnice 5, 128 53 Prague 2, Czech Republic. Phone: (+420) 224 965 864; Fax: (+420) 224 965 916; e-mail: jan.molinsky@seznam.cz

Received October 20, 2012. Accepted October 22, 2012.

Original Article

Galantamine as a Preventive of Diisopropylphosphorofluoridate Toxicity Effects in Rat Brain

(diisopropylfluorophosphate / galantamine / DFP seizures / c-fos mRNA / acetylcholinesterase)

M. M. Saghafi , M. Živin , P. Pregelj

University of Ljubljana, Medical Faculty, Institute of Pathophysiology, Brain Research Laboratory, Ljubljana, Slovenia.

Pages: 32 - 40 (PDF)

Corresponding author: Peter Pregelj, University of Ljubljana, Medical Faculty, Institute of Pathophysiology, Brain Research Laboratory, Zaloska 4, 1000 Ljubljana, Slovenia. Phone: (+386) 41 691 512 ; Fax: (+386) 1 543 7021; e-mail: peter.pregelj@psihklinika.si

Received March 9, 2012. Accepted November 23, 2012.

Short Communication

Rapid Isolation of Lysosomal Membranes from Cultured Cells

(lysosomes / lysosomal membrane / methionine methyl ester / gradient centrifugation)

D. Muš álková, J. Lukáš, F. Majer, O. Hřebíček , E. Svobodová, L. Kuchař , J. Honzíková, H. Hůlková, J. Ledvinová, M. Hřebíček

Institute of Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic

Pages: 41 - 46 (PDF)

Corresponding author: Martin Hřebíček, Institute of Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Ke Karlovu 2, Prague 2, Czech Republic. Phone: (+420) 2 24967208; Fax: (+420) 2 2496 7119; e-mail: martin.hrebicek@lf1.cuni.cz

Received February 8, 2012. Accepted June 26, 2012.

Short Communication

Validation of RNA Extraction Procedures Focused on Micro RNA Expression Analysis

(RNA preparation / miRNA / RIN)

M. Remáková, M. Škoda, M. Faustov á, J. Vencovský, P. Novota

Department of Experimental and Clinical Rheumatology, Institute of Rheumatology, Prague, Czech Republic

Pages: 47 - 50 (PDF)

Corresponding author: Peter Novota, Department of Experimental and Clinical Rheumatology, Institute of Rheumatology, Na Slupi 4, 128 50 Prague, Czech Republic. Phone: (+420) 234 075 319; Fax: (+420) 224 914 451; e-mail: novota@revma.cz

Received June 27, 2112. Accepted July 16, 2012.

Correction and Addendum

Correction of “Eliášová I, Mazura I, Smejtek L.: DNA analysis of ancient skeletal remains, Folia Biol(Praha), 2010;56(2):47-50”.

Acknowledgement

The authors thank Dr. Daniel Vaněk for his generous support, advice, providing the necessary equipment and chemicals for the study and apologize for omitting to acknowledge adequately this important contribution.

Pages: 51 (PDF)