Volume 61 (2015) No. 6

 

Review Article

Circulating MicroRNAs: Methodological Aspects in Detection of These Biomarkers

(circulating miRNAs / molecular biomarkers / intercellular communication / body fluids)

A. HRUŠTINCOVÁ, H. VOTAVOVÁ, M. DOSTÁLOVÁ MERKEROVÁ

Department of Genomics, Institute of Hematology and Blood Transfusion, Prague, Czech Republic

Pages: 203 -218 (PDF)

Corresponding author: Michaela Dostálová Merkerová, Institute of Hematology and Blood Transfusion, U Nemocnice 1, 128 20 Prague 2, Czech Republic. Phone: (+420) 221977231; Fax: (+420) 221977371; e-mail: michaela.merkerova@uhkt.cz


Original Article

Hepatoerythropoietic Porphyria Caused by a Novel Homoallelic Mutation in Uroporphyrinogen Decarboxylase Gene in Egyptian Patients

(hepatoerythropoietic porphyria / HEP / uroporphyrinogen decarboxylase / UROD / skin photosensitivity / red urine)

M. S. FARRAG1, I. MIKULA1, E. RICHARD2,3, V. SAUDEK4, H. DE VERNEUIL2,3, P. MARTÁSEK1

1Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic

2University of Bordeaux, 3INSERM U1035, Bordeaux, France

4University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK

Pages: 219 -226 (PDF)

Corresponding author: Pavel Martásek, Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague. Ke Karlovu 2, 121 00 Prague 2, Czech Republic. Phone: (+420) 602 935 339; Fax: (+420) 224967099; e-mail: pavel.martasek@gmail.com


Original Article

A Novel Mutation in the FECH Gene in a Czech Family with Erythropoietic Protoporphyria and a Population Study of IVS3-48C Variant Contributing to the Disease

(hepatoerythropoietic porphyria / HEP / uroporphyrinogen decarboxylase / UROD / skin photosensitivity / red urine)

M. S. FARRAG1, J. KUČEROVÁ1, L. ŠLACHTOVÁ1, O. ŠEDA2, J. ŠPERL3, P. MARTÁSEK1

1Department of Paediatrics and Adolescent Medicine, 2Institute of Biology and Genetics, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic

3Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

Pages: 227 -232 (PDF)

Corresponding author: Pavel Martásek, Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Ke Karlovu 2, 121 00 Prague 2, Czech Republic. Phone: (+420) 602 935 339; Fax: (+420) 224 967 099; e-mail: pavel.martasek@gmail.com


Original Article

Oestradiol Treatment Counteracts the Effect of Fructose-Rich Diet on Matrix Metalloproteinase 9 Expression and NFκB Activation

(fructose-rich diet / matrix metalloproteinase 9 / NFκB / oestradiol / heart / rat)

M. BUNDALO1, M. ZIVKOVIC1, T. CULAFIC2, M. STOJILJKOVIC2, G. KORICANAC2, A. STANKOVIC1

1Laboratory for Radiobiology and Molecular Genetics, 2Laboratory for Molecular Biology and Endocrinology, Vinca Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia

Pages: 233 -240 (PDF)

Corresponding author: Aleksandra Stankovic, Vinca Institute of Nuclear Sciences, University of Belgrade, Laboratory for Radiobiology and Molecular Genetics, PO Box 522, 11000 Belgrade, Serbia. Phone: (+ 381) 11 3408 566; Fax: (+ 381) 11 644 7485; e-mail: alexas@vinca.rs


Original Article

Immune Function Alterations during 12 Weeks of Abstinence in Heroin Users

(heroin user / abstinence / immune)

Z. WANG1, X-R. YANG1, H. SONG1, B-R. CAO1, F. YIN2, Z-M. AN1, L. KANG1, J. LI1

1West China Hospital, 2West China School of Public Health, Si Chuan University, Cheng Du, Si Chuan, China

Pages: 241 -246 (PDF)

Corresponding author: Jing Li and Lin Kang, West China Hospital, Sichuan University, No.28 Dian Xin Nan Jie, Chengdu 610041, Sichuan P.R. China. Jing Li: Phone: (+86) 18980601715; Fax: (+8) 62885422633; e-mail: joana028@163.com. Lin Kang: Phone: (+86) 18980602031; e-mail: ruoyukang@163.com