Volume 65 (2019) No. 1

Review Article

Fluorescent Probes for Monitoring Cholesterol Trafficking in Cells

(cholesterol, sterol / cholesterol analogues / fluorescent probes / trafficking / cellular transport)

J. KRÁLOVÁ1, V. KRÁL2

1CZ-OPENSCREEN, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic

2University of Chemistry and Technology, Prague, Czech Republic

Pages: 1 - 10 (PDF)

Corresponding author: Jarmila Králová, CZ-OPENSCREEN, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, 14220 Prague 4, Czech Republic. E-mail: kralova@img.cas.cz


Review Article

Genes and Mechanisms Responsible for Expansion of Acute Myeloid Leukaemia Blasts

(acute myeloid leukaemia / bone marrow / leukaemic stem cells / leukaemic blasts / recurrent gene mutations / mechanisms of malignant transformation)

M. Dvořák, M. Dvořáková

Department of Cell Differentiation, Institute of Molecular Genetics of the ASCR, v. v. i., Prague,
Czech Republic

Pages: 11 - 23 (PDF)

Corresponding author: Michal Dvořák, Department of Cell Differentiation, Institute of Molecular Genetics of the ASCR, v. v. i., Vídeňská 1083, 142 20 Prague 4, Czech Republic. E-mail: mdvorak@img.cas.cz


Original Article

Genistein and Selected Phytoestrogen-Containing Extracts Differently Modulate Antioxidant Properties and Cell Differentiation: an in Vitro Study in NIH-3T3, HaCaT and MCF-7 Cells

(Trifolium pratense L. / Glycine max L. / isoflavonoids / cytotoxicity / wound healing / tumour growth /
breast cancer)

I. Šušaníková1, M. Puchľová1, V. Lachová1, E. Švajdlenka2, P. Mučaji1, K. Smetana Jr.3,4, P. Gál1,5,6,7

1Department of Pharmacognosy and Botany, 2Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic

3Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic

4BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic

5Laboratory of Cell Interactions, MediPark, Pavol Jozef Šafárik University in Košice, Košice, Slovak Republic

6Department of Biomedical Research, East-Slovak Institute of Cardiovascular Diseaes, Inc., Košice,
Slovak Republic

7Burn Centre Prague, Third Faculty of Medicine, Charles University, Prague, Czech Republic

Pages: 24 - 35 (PDF)

Corresponding author: Peter Gál, Department of Biomedical Research, East-Slovak Institute of Cardiovascular Diseases, Inc., Ondavská 8, 040 11 Košice, Slovak Republic. Fax: (+421) 55 789

1613; e-mail: pgal@vusch.sk

or

Ivana Šušaníková, Department of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, 832 32 Bratislava, Slovak Republic. e-mail: susanikova1@uniba.sk

Michal Dvořák, Department of Cell Differentiation, Institute of Molecular Genetics of the ASCR, v. v. i., Vídeňská 1083, 142 20 Prague 4, Czech Republic. E-mail: mdvorak@img.cas.cz

Original Article

Cardiac Enlargement in the Chick Embryo Induced by Hypothermic Incubation Is Due to a Combination
of Hyperplasia and Hypertrophy of Cardiomyocytes

(embryonic heart / cell size / cell proliferation / immunofluorescence)

K. SKUHROVÁ1, A. KVASILOVÁ1, J. SVATŮŇKOVÁ2, D. SEDMERA1,2

1Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic

2Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic

Pages: 36 - 42 (PDF)

Corresponding author: David Sedmera, Institute of Anatomy, First Faculty of Medicine, Charles University, U Nemocnice 3, 128 00 Prague 2, Czech Republic. e-mail: david.sedmera@lf1.cuni.cz



Original Article

Trichostatin A Inhibits Rhabdomyosarcoma Proliferation and Induces Differentiation through MyomiR Reactivation

(rhabdomyosarcoma / TsA / muscle differentiation / myomiR / miRNA)

M. TARNOWSKI, M. TKACZ, P. KOPYTKO, J. BUJAK, K. PIOTROWSKA, A. PAWLIK

Department of Physiology, Pomeranian Medical University, Szczecin, Poland

Pages: 43 - 52 (PDF)

Corresponding author: Maciej Tarnowski, Department of Physiology, Pomeranian Medical University, al. Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland. Phone: (+91) 466 16 21; e mail: maciejt@pum.edu.pl