Volume 56 (2010) No. 2
Original Article
PI3K/Akt Promotes GRP78 Accumulation and Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis in HEK293 Cells
(ER stress / PI3K/Akt / GRP78 / apoptosis / HEK293 cells)
R. Y. DAI1,2, S. K. CHEN3, D. M. YAN1, R. CHEN4, Y. P. LIU1, C. Y. DUAN1, J. LI2, T. HE2, H. LI1,2
1Department of Biochemistry, 3Department of Biology, 4Department of Public Health, Luzhou Medical College, Luzhou, Sichuan, P.R. China
2Key Laboratory of Sichuan Colleges and Universities for Human Disease Cell Signalling and Regulation, Luzhou, Sichuan, P.R. China
Pages: 37 - 46 (PDF)
Corresponding author: Hong Li, Key Laboratory of Sichuan Colleges and Universities for Human Disease Cell Signalling and Regulation, Luzhou 646000, Sichuan, P.R. China. e-mail: lihong7188(zavinac)163.com
Received December 21, 2009. Accepted March 8, 2010.
Original Article
DNA Analysis of Ancient Skeletal Remains
(ancient DNA / advanced-glycation end-products / amelogenin / STR analysis / settlement at Kněževes)
I. ELIAŠOVA1, I. MAZURA1, L. SMEJTEK2
1Charles University in Prague, Faculty of Science, Department of Anthropology and Human Genetics, Prague, Czech Republic
2Institute for Archaeological Heritage of Central Bohemia, Prague, Czech Republic
Pages: 47 - 50 (PDF)
Corresponding author: Irena Eliašova, V Podluži 5, 140 00 Prague 4, Czech Republic. Phone: (+420) 606 473 993; Fax: (+420) 241 742 377; e-mail: i.eliasova(zavinac)seznam.cz
Received May 27, 2009. Accepted June 8, 2009.
Original Article
CCAAT/Enhancer-Binding Protein α (CEBPA) Polymorphisms and Mutations in Healthy Individuals and in Patients with Peripheral Artery Disease, Ischaemic Heart Disease and Hyperlipidaemia
(CEBPA gene / C/EBPα protein / hyperlipidaemia / ischaemic heart disease / mutation / peripheral artery disease / polymorphism)
O. FUCHS1, A. KOSTEČKA1, D. PROVAZNIKOVA1, B. KRASNA1, R. KOTLIN1, M. STAŇKOVA1, P. KOBYLKA1, G. DOSTALOVA2, M. ZEMAN3, M. CHOCHOLA2
1Department of Cell Physiology, Institute of Haematology and Blood Transfusion, Prague, Czech Republic
Charles University in Prague, First Faculty of Medicine and General University Hospital, 22nd Department of Internal Medicine, 34th Department of Internal Medicine, Prague, Czech Republic
Pages: 51 - 57 (PDF)
Corresponding author: Ota Fuchs, Institute of Haematology and Blood Transfusion, Department of Cell Physiology, U Nemocnice 1, 128 20 Prague 2, Czech Republic. Phone: (+420) 221 977 313; Fax: (+420) 221 977 370; e-mail: Ota.Fuchs(zavinac)uhkt.cz.
Received July 10, 2009. Accepted August 27, 2009.
Original Article
Impairment of Sox9 Expression in Limb Buds of Rats Homozygous for Hypodactyly Mutation
(limb development / hypodactyly / Sox9 / Bmp signaling / the Norway rat)
F. LIŠKA1, P. ŠNAJDR2, S. STRICKER3, C. GOSELE4, D. KŘENOVA1, S. MUNDLOS3, N. HUBNER4
Charles University in Prague, First Faculty of Medicine: 1Institute of Biology and Medical Genetics; 2Institute of Anatomy, Prague, Czech Republic
3Max-Planck-Institute for Molecular Genetics, Berlin, Germany
4Max-Delbruck-Center for Molecular Medicine (MDC), Berlin, Germany
Pages: 58 - 65 (PDF)
Corresponding author: František Liška, Charles University in Prague, First Faculty of Medicine, Institute of Biology and Medical Genetics, Albertov 4, 128 00 Prague 2, Czech Republic. Phone: +420 224 968 154; Fax: +420 224 918 666; e-mail: frantisek.liska(zavinac)lf1.cuni.cz
Received June 16, 2009. Accepted June 18, 2009.
Original Article
New Luminescence-Based Approach to Measurement of Luciferase Gene Expression Reporter Activity and Adenosine Triphosphate-Based Determination of Cell Viability
(cell viability / reporter gene assay / luciferase / adenosine triphosphate)
R. KONOPKA1, M. HYŽĎALOVA1, L. KUBALA1, J. PACHERNIK2
1Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic
2Institute of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic
Pages: 66 - 71 (PDF)
Corresponding author: Lukaš Kubala, Institute of Biophysics, Academy of Sciences of the Czech Republic, Kralovopolska 135, 612 65 Brno, Czech Republic. Phone: (+420) 541 517 117; Fax: (+420) 541 211 293; e-mail: kubalal(zavinac)ibp.cz
Received June 23, 2009. Accepted August 10, 2009.
Original Article
Leflunomide Derivate FK 778 in Accelerated Renal Injury in Transgenic Rat
(ischaemia/reperfusion injury / FK 778 / leflunomide / transgenic rat / chronic allograft nephropathy / hypertension)
S. BLOUDIČKOVA1, J. RAJNOCH1, A. LODEREROVA2, E. HONSOVA2, O. VIKLICKY1
1Department of Nephrology, Transplant Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
2Department of Pathology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
Pages: 71 - 77 (PDF)
Corresponding author: Silvie Bloudičkova, Department of Nephrology, Transplant Centre, Institute for Clinical and Experimental Medicine, Videňska 1958/9, 140 21 Prague 4, Czech Republic. Phone: (+420) 261364110; Fax: (+420) 261363113; e-mail: sibl(zavinac)medicon.cz
Received July 12, 2009. Accepted December 12, 2009.
Short Communication
Response Surface Optimization of the Critical Medium Components for the Production of α-Galactosidase from Aspergillus parasiticus MTCC-2796
(α-galactosidase / culture condition / Aspergillus parasiticus / submerged fermentation / response surface methodology)
K. SHIVAM, S. K. MISHRA
Department of Biotechnology, D. D. U. Gorakhpur University, Gorakhpur, India
Pages: 78 - 82 (PDF)
Corresponding author: Kumar Shivam, Department of Biotechnology, D.D.U.Gorakhpur University, Gorakhpur-273009, U. P., India.Phone: +91-9452450495; e-mail: k.shivam(zavinac)rediffmail.com
Received April 20, 2009. Accepted September 25, 2009.
