Volume 56 (2010) No. 5
Original Article
Reversal of Hypermethylation and Reactivation of the RARβ2 Gene by Natural Compounds in Cervical Cancer Cell Lines
(cytotoxicity / dietary polyphenols / demethylation / IC50 / MSP)
A. K. JHA1, M. NIKBAKHT1, G. PARASHAR1, A. SHRIVASTAVA2, N. CAPALASH1*,J. KAUR1*
1Department of Biotechnology, Panjab University, Chandigarh, India
2Department of Zoology, University of Delhi, Delhi, India
*The authors contributed equally
Pages: 195 - 200 (PDF)
Corresponding author: Jagdeep Kaur, Department of Biotechnology, Panjab University, Sector-14, Chandigarh-160014, India. Phone: (+91) 172-2534086; Fax: (+91) 172-2541409; e-mail: jagsekhon@yahoo.com
Received July 6, 2010. Accepted September 9, 2010.
The Effect of a Histone Deacetylase Inhibitor – Valproic Acid – on Nucleoli in Human Leukaemic Myeloblasts
(nucleoli / histone deacetylase inhibitor / leukaemic myeloblasts)
K. SMETANA1, M. ZÁPOTOCKÝ2
1Institute of Haematology and Blood Transfusion, Prague, Czech Republic
2Charles University in Prague, 2nd Faculty of Medicine, Prague, Czech Republic
Pages: 201 - 205 (PDF)
Corresponding author: Karel Smetana, Institute of Haematologyand Blood Transfusion, U nemocnice 1, Prague 2, 128 20, Czech Republic. Phone: (+420) 221 977 271; Fax: (+420) 221 977 249; e-mail: karel.smetana@uhkt.cz
Received May 24, 2010. Accepted June 17, 2010.
Th1/Th2 Cytokine Gene Polymorphisms in Patients With Uterine Fibroid
(uterine fibroid / myoma / cytokine / gene polymorphism)
O. SOSNA1, L. KOLESÁR2, A. SLAVČEV2, J. SKIBOVÁ3, T. FAIT1, M. MARA1,I. STŘÍŽ4, D. KUŽEL1
1Charles University in Prague, First Faculty of Medicine and General University Hospital, Department of Gynaecology and Obstetrics, Prague, Czech Republic
Institute for Clinical and Experimental Medicine: 2Department of Immunogenetics, 3Department of Medical Statistics, 4Department of Clinical and Transplant Immunology, Prague, Czech Republic
Pages: 206 - 210 (PDF)
Corresponding author: Libor Kolesár, Department of Immunogenetics, IKEM, Vídeňská 1958/9, 140 21 Prague, Czech Republic; e-mail: libor.kolesar@ikem.cz
Received April 19, 2010. Accepted May 10, 2010.
The Expression of NADPH Oxidases and Production of Reactive Oxygen Species by Human Lung Adenocarcinoma Epithelial Cell Line A549
(lung epithelial cells / reactive oxygen species / fluorometry / chemiluminescence)
H. KOLÁŘOVÁ1, L. BINÓ1,2, K. PEJCHALOVÁ1, L. KUBALA1
1Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic
2Institute of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic
Pages: 211 - 217 (PDF)
Corresponding author: Lukáš Kubala, Institute of Biophysics,Academy of Sciences of the Czech Republic, Královopolská 135,612 65 Brno, Czech Republic. Phone: (+420) 541 517 117; Fax:(+420) 541 211 293; e-mail: kubalal@ibp.cz
Received July 28, 2009. Accepted August 20, 2010.
Why We Are Not Able to Find the Coronary Heart DiseaseGene – apoE As an Example
(apoprotein E / cardiovascular risk /gene polymorphism / myocardial infarction)
R. POLEDNE1,2, J. A. HUBÁČEK1,2, V. STANĚK1, M. ASCHERMANN3,J. MATOUŠKOVÁ5, J. VESELKA4, P. WIDIMSKÝ6, R. CÍFKOVÁ1, V. LÁNSKÁ1,J. PIŤHA1,2
1Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic
2Centre for Cardiovascular Research, IKEM, Prague, Czech Republic
3Charles University in Prague, First Faculty of Medicine and General University Hospital, 2nd Departmentof Medicine – Department of Cardiovascular Medicine, Prague, Czech Republic
4Charles University in Prague, Second Faculty of Medicine and Motol University Hospital, Departmentof Cardiology, Prague, Czech Republic
5Department of Cardiology, Na Homolce Hospital, Prague, Czech Republic
6Charles University in Prague, Third Faculty of Medicine and Královské Vinohrady University Hospital,Cardiocenter, Department of Cardiology, Prague, Czech Republic
Pages: 218 - 222 (PDF)
Corresponding author: Rudolf Poledne, IKEM, Vídeňská 1958/9,140 21 Prague 4, Czech Republic. Phone: (+420) 261 362 729;Fax: +420 241 721 574; e-mail: rudolf.poledne@ikem.cz
Received February 10, 2010. Accepted March 8, 2010.
Short Communication
The Assessment of Array Comparative Genomic Hybridizationin Complex Karyotype Analyses
(array comparative genomic hybridization / multicolour fluorescence in situ hybridization / myelodysplasticsyndromes / complex karyotype)
D. BYSTŘICKÁ1, Z. ZEMANOVÁ1, J. BŘEZINOVÁ2, M. GANČARČÍKOVÁ1,L. GROSOVÁ1, I. ŠÁROVÁ2, S. IZÁKOVÁ2, A. BERKOVÁ1, K. MICHALOVÁ1,2
1Charles University in Prague, First Faculty of Medicine and General University Hospital, Institute ofClinical Biochemistry and Laboratory Diagnostics, Center of Oncocytogenetics, Prague, Czech Republic2Institute of Haematology and Blood Transfusion, Prague, Czech Republic
Pages: 223 - 230 (PDF)
Corresponding author: Dagmar Bystřická, Charles University inPrague, First Faculty of Medicine and General University Hospital,Institute of Clinical Biochemistry and Laboratory Diagnostics,Center of Oncocytogenetics, U nemocnice 2, 128 08 Prague2, Czech Republic. e-mail: Dagmar.Bystricka@vfn.cz
Received January 4, 2010. Accepted January 26, 2010.
