Volume 58 (2012) No. 5
Original Article
Dynamics and Morphology of Focal Adhesions in Complex 3D Environment
(focal adhesions, 3D, dermis-based matrix, adhesion, migration)
O. Tolde1,3, D. Rösel1, R. Janoštiak1, P. Veselý2, J. Brábek1
1Department of Cell Biology, Faculty of Science, Charles University in Prague, Czech Republic
2CEITEC – Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic3Department of Molecular Medicine, Max Planck Institute of Biochemistry, Martinsried, Germany.
Corresponding author: Jan Brábek, Department of Cell Biology, Faculty of Science, Charles University in Prague, Viničná 7, 128 43 Prague 2, Czech Republic. Phone: (+420) 22195 1769; Fax: (+420) 22195 1761; e-mail: brabek@natur.cuni.cz
Received May 24, 2012. Accepted June 18, 2012.
Original Article
Low Expression of NQO1 Predicts Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer Patients Treated with TAC Regimen
(breast cancer / neoadjuvant therapy / predictive biomarkers)
J. Grim1, P. Jandík3, I. Slánská1, E. Doleželová-Brčáková4, L. Fuksa4, A. Ryška2, J. Knížek5, J. Petera1, S. Mičuda4, H. Hornychová2
1Department of Oncology and Radiotherapy, 2Department of Pathology, 3Department of Surgery, Charles University in Prague, Faculty of Medicine and University Teaching Hospital in Hradec Králové, Czech Republic
4Department of Pharmacology, 5Department of Medical Biophysics, Charles University in Prague, Faculty of Medicine in Hradec Králové, Czech Republic
Corresponding author: Jiří Grim, Department of Oncology and Radiotherapy, University Teaching Hospital in Hradec Králové, Sokolská 581, 500 05 Hradec Králové, Czech Republic. Phone: (+420) 495 834 666; e-mail: grimj@lfhk.cuni.cz
Received February 13, 2012. Accepted May 14, 2012.
Original Article
Influence of Platelet γ-Glutamyltransferase on Oxidative Stress and Apoptosis in the Presence of Holo-Transferrin
(platelet / γ-glutamyltransferase / transferrin / apoptosis / oxidative stress)
A. Sener1, O. Cevik1, G. Yanikkaya- Demirel2, S. Apikoglu-Rabus3, D. Ozsavci1
1Biochemistry Department, 3Clinical Pharmacy Department, Faculty of Pharmacy, Marmara University, Istanbul, Turkey
2Microbiology-Immunology Department, Faculty of Medicine, Yeditepe University, Istanbul, Turkey
Corresponding author: Azize Sener, Biochemistry Department, Faculty of Pharmacy, Marmara University, Tibbiye Cad., No. 49, 34668, Haydarpasa-Istanbul, Turkey. e-mail: azizesener@hotmail.com
Received February 13, 2012. Accepted May 13, 2012.
Original Article
Association between a Marker on Chromosome 9 and Acute Coronary Syndrome Confirmatory Study on Czech Population
(acute coronary syndrome / ANRIL / polymorphism / chromosome 9 / CDKN2A / CDKN2B)
J. A. HUBÁČEK1, V. STANĚK1, M. GEBAUEROVÁ1, R. POLEDNE1, M. ASCHERMANN2, H. SKALICKÁ2, J. MATOUŠKOVÁ3, A. KRUGER3, M. PĚNIČKA4, H. HRABÁKOVÁ4, J. VESELKA5, P. HÁJEK5, V. LÁNSKÁ1, V. ADÁMKOVÁ1,6, J. PIŤHA1
1Institute for Clinical and Experimental Medicine, Prague, Czech Republic
22nd Department of Internal Medicine, General University Hospital, Prague, Czech Republic
3Department of Cardiology, Homolka Hospital, Prague, Czech Republic
4Cardiocenter, Department of Cardiology, University Hospital Královské Vinohrady, Prague, Czech Republic
5Department of Cardiology, Teaching Hospital Motol, Prague, Czech Republic
6University of South Bohemia, Faculty of Health and Social Studies, České Budějovice, Czech Republic
Corresponding author: Jaroslav A. Hubáček, IKEM-DEM-LMG, Vídeňská 1958/9, 140 21 Prague 4, Czech Republic. Phone: (+420) 261 363 379; Fax: (+420) 241 721 666; e-mail: jahb@ikem.cz
Original Article
Transcriptional Activity of Tumour Necrosis Factor α (TNF-α) in Patients with Subclinical Coronary Atherosclerosis – Preliminary Results
(tumour necrosis factor α / subclinical atherosclerosis)
J. Dąbek1, R. Świderski1, J. Głogowska-Ligus2, P. Pysz1
1Department of Cardiology, 2Department of Epidemiology, Medical University of Silesia in Katowice, Poland
Corresponding author: Joanna Głogowska-Ligus, Department of Epidemiology, Medical University of Silesia, Piekarska 18, 41-902 Bytom, Poland. Phone: (+48) 32 397 65 31; e-mail: jglogowska@sum.edu.pl
Received March 28, 2012. Accepted April 30, 2012.
Short Communication
Testing Chemical Agents with the Cytokinesis-Block Micronucleus Cytome Assay
(C3A cells / genotoxicity / chemical mutagens / spindle poisons / clastogens / enzyme inhibitors)
A. Maes1, R. Anthonissen1, L. Verschaeve1,2
1Scientific Institute of Public Health, O.D. Public Health and Surveillance, Laboratory of Toxicology, Brussels, Belgium
2Department of Biomedical Research, University of Antwerp, Antwerp, Belgium
Corresponding author: Luc Verschaeve, Scientific Institute of Public Health, O.D. Public Health and Surveillance, Laboratory of Toxicology, J. Wytsmanstreet 14, B-1050 Brussels, Belgium. Phone: +32 2 642 54 36; Fax: +32 2 642 52 24; e-mail: luc.verschaeve@wiv-isp.be
Received January 4, 2012. Accepted April 2, 2012.
