Volume 59 (2013) No. 6

Review Article

Phylogeny, Regeneration, Ageing and Cancer: Role of Microenvironment and Possibility of Its Therapeutic Manipulation

(evolution / regeneration / ageing / cancer / tumour microenvironment)

K. Smetana, Jr.1, B. Dvořánková1, L. Lacina1,2

1Institute of Anatomy, First Faculty of Medicine, Charles University in Prague, Czech Republic

2Institute of Medical Biology, A*STAR, Singapore

Pages: 207 - 216 (PDF)

Corresponding author: Karel Smetana, Institute of Anatomy, First Faculty of Medicine, Charles University in Prague, U nemocnice 3, 128 00 Prague 2, Czech Republic. e-mail: karel.smetana@lf1.cuni.cz

Original Article

Correlated Increase of Omentin-1 and Adiponectin by Exenatide, Avandamet and Dietary Change in Diet-Induced Obese Rats

(exenatide / avandamet / dietary change / obesity / adipokines)

W.-H. Feng1, X.-W. Yuan2, G.-Y. Tong1, W.-M. Wang1, Y. Hu1, S.-M. Shen1, P. Li1, Y. Bi1, J. Hu1, L.-L.  Shao3, Y.-Y. Dai4, Y.-Q. Liu4, S.-K. Xiang5, D.-H. Yang1, D.-L. Zhu1

1Department of Endocrinology, Drum Tower Hospital Affiliated to Nanjing Medical University, Nanjing, China

2Department of Endocrinology, Nanjing Children’s Hospital Affiliated to Nanjing Medical University, Nanjing, China

3Nanjing University of Chinese Medicine, Nanjing, China

4Medical School of Southeast University, Nanjing, China

5Department of Endocrinology, Changzhou First People’s Hospital, Nanjing, China

Pages: 217 - 224 (PDF)

Corresponding author: Da-Long Zhu, Department of Endocrinology, Drum Tower Hospital Affiliated to Nanjing Medical University, Zhongshan Road 321, 210008, Nanjing, China. Phone: 86- 25-83106666-61432; Fax: 86-25-83105313; e-mail: zhudalong@nju.edu.cn

Original Article

Protective Effect of the Nitric Oxide Pathway in L-Citrulline Renal Ichaemia-Reperfusion Injury in Rats

(L-citrulline / ischaemia-reperfusion / nitric oxide synthase / L-NAME)

X. Fu1, S. Li1, G. Jia1, L. Gou1, X. Tian1, L. Sun1, X. Ling1, N. Lan1, X. Yin1, R. Ma3, L. Liu2, Y. Liu1

1School of Pharmacy, Xuzhou Medical College, 2Xuzhou Environmental Monitoring Station, Xuzhou, P. R. China

3School of Environment, Nanjing University, Nanjing, P. R. China

Pages: 225 - 232 (PDF)

Corresponding author: Yi Liu and Li Liu, School of Pharmacy, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, 221004 Jiangsu, P. R. China. Phones: (+86) 516 83262136 (Yi Liu), (+86) 516 82365092 (Li Liu). e-mails: cbpe201087@gmail.com (Yi Liu), ppmll@sina.com (Li Liu)

Original Article

Stress Perception and (GT)n Repeat Polymorphism in Haem Oxygenase 1 Promoter Are Both Risk Factors in Development of Eating Disorders

(haem oxygenase 1 / eating disorders / stress / anorexia / gene environment interactions)

L. Šlachtová1, D. Kaminská2, M. Chvál3, L. Králík1, P. Martásek1, H. Papežová2

1Department of Paediatrics and Adolescent Medicine, 2Department of Psychiatry, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic

3Institute for Research and Development of Education, Faculty of Education, Charles University in Prague, Czech Republic

Pages: 233 - 239 (PDF)

Corresponding author: Pavel Martásek, Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Ke Karlovu 2, 128 08 Prague 2, Czech Republic. E-mail: pavel.martasek@gmail.com

Original Article

Hypermethylation of RAD51L3 and XRCC2 Genes to Predict Late Toxicity in Chemoradiotherapy-Treated Cervical Cancer Patients

(DNA methylation / RAD51 gene family / cervical cancer / late toxicity)

S. Paulíková1, M. Chmelařová2, J. Petera1, V. Palička2, A. Paulík1

1Department of Oncology and Radiotherapy, 2Department of Clinical Biochemistry and Diagnostics, Charles University in Prague – Faculty of Medicine in Hradec Králové and Faculty Hospital Hradec  Králové, Czech Republic

Pages: 240 - 245 (PDF)

Corresponding author: Simona Paulíková, Department of Oncology and Radiotherapy, Charles University in Prague – Faculty of Medicine in Hradec Králové and Faculty Hospital Hradec Králové, Sokolská 581, 50005, Hradec Králové, Czech Republic. Phone: (+420) 495 832 176; e-mail: simonabrokesova@seznam.cz

Original Article

Association of Gln223Arg Polymorphism of the Leptin Receptor with Hypertensive Left Ventricular Hypertrophy

(leptin receptor / hypertension / polymorphism / left ventricular hypertrophy)

H. Zheng1, N. Xie1, H. Xu2, J. Huang1, X. Xie1, M. Luo1

1Geriatrics Department, 2Cardiology Department, Tongji Hospital Affiliated to Tongji University,  Shanghai, China

Pages: 246 - 252 (PDF)

Corresponding author: Ming Luo, 389 Xincun Road, Shanghai, P.R. China, 200065. ; Phone: 0086-21-66111282; Fax: 0086-21-56050502; e-mail:lmfc2013@163.com