Volume 60 (2014) No. 3

Original Article

Rho GTPase Rac1: Molecular Switch within the Galectin Network and for N-Glycan α2,6‑Sialylation/O-Glycan Core 1 Sialylation in Colon Cancer in Vitro

(apoptosis / cancer / glycosylation / invasion / lectin / migration)

S. ANDRÉ1, T. SINGH1, J. C. LACAL2, K. SMETANA Jr3, H.-J. GABIUS1

1Ludwig-Maximilians-University Munich, Faculty of Veterinary Medicine, Institute of Physiological Chemistry, Munich, Germany

2Instituto de Investigaciones Biomédicas, CSIC, Madrid, Spain

3Institute of Anatomy, First Faculty of Medicine, Charles University in Prague, Czech Republic 

Pages: 95 - 107 (PDF)

Corresponding author: Hans-Joachim Gabius, Ludwig-Maximilians-University Munich, Faculty of Veterinary Medicine, Institute of Physiological Chemistry, Veterinarstrasse 13, D-80539 Munich, Germany. Phone: + 049-(0)89-2180-2290; e.mail: gabius@tiph.vetmed.uni-muenchen.de or gabius@lectins.de


Original Article

An Association between MPO -463 G/A Polymorphism and Type 2 Diabetes

(MPO / oxidation / polymorphism / risk)

A. Ergen1, H. Karagedik1, Z. E. Karaali2, T. Isbir3

1Istanbul University, The Institute of Experimental Medicine, Department of Molecular Medicine, Capa-Istanbul, Turkey

2Department of Internal Medicine, Haseki Training and Research Hospital, Istanbul, Turkey

3Department of Medical Biology, Yeditepe University, Faculty of Medicine, Istanbul, Turkey

Pages: 108 - 112 (PDF)

Corresponding author: Arzu Ergen, Department of Molecular Medicine, The Institute of Experimental Medicine, Istanbul University, 34280 Capa-Istanbul, Turkey. Phone: (+90) 212 414 20 00/33331; e-mail: a_ergen@yahoo.com

 

Original Article

Differential Expression and Processing of Matrix Metalloproteinase 19 Marks Progression of  Gastrointestinal Diseases 

(matrix metalloproteinase 19 / inflammatory bowel disease / macrophages / colon cancer / endothelium / lymphatic vessels)

M. Červinková1, P. Horák2, I. Kanchev1, R. Matěj3, J. Fanta2, R. Sequens4, P. Kašpárek1,5, L. Sarnová1, J. Turečková1, R. Sedláček1

1Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the ASCR, v. v. i., Prague, Czech Republic 

2Department of Surgery, First Faculty of Medicine, Charles University in Prague and Na Bulovce Hospital, Prague, Czech Republic

3Department of Pathology and Molecular Medicine, Thomayer Hospital, Prague, Czech Republic

4Gastroenterology Surgical Centre, Hospital of Merciful Sisters of St. Borromeo, Prague, Czech Republic 

5Department of Genetics and Microbiology, Faculty of Sciences, Charles University in Prague, Czech Republic

Pages: 113 - 122 (PDF)

Corresponding author: Radislav Sedláček, Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the ASCR, v. v. i., Vídeňská 1083, 142 20 Prague 4, Czech Republic. Phone: (+420) 24106 3137; Fax: (+420) 22431 0955; e-mail: radislav.sedlacek@img.cas.cz.

 

Original Article

Time Course of Cerebral Hypoperfusion-Induced Neurodegenerative Changes in the Cortex of Male and Female Rats

(neurodegeneration / apoptosis / cerebral hypoperfusion / cerebral cortex / rat) 

M. STANOJLOVIĆ1, A. HORVAT1, I. GUŠEVAC1, I. GRKOVIĆ1, N. MITROVIĆ1, I. BUZADŽIĆ2, D. DRAKULIĆ1

1Laboratory of Molecular Biology and Endocrinology, VINCA Institute of Nuclear Sciences, University of Belgrade, Serbia 

2Department of Human Genetics and Prenatal Diagnostics, ZVEZDARA University Medical Hospital, Belgrade, Serbia

Pages: 123 - 132 (PDF)

Corresponding author: Dunja Drakulić, Laboratory of Molecular Biology and Endocrinology, VINCA Institute of Nuclear Sciences, University of Belgrade, P.O. Box 522, 11001 Belgrade, Serbia. E-mail:drakulic@vinca.rs


Original Article

HNF-4α Regulates Expression of Human Ornithin Carbamoyltransferase through Interaction with Two Positive Cis-Acting Regulatory Elements Located in the Proximal Promoter

(ornithine carbamoyltransferase / OTC / HNF-4α / transcription / regulation / promoter / DNase I footprinting / EMSA)

O. Lukšan1, L. Dvořáková2, M. Jirsa1

1Laboratory of Experimental Hepatology, Institute for Clinical and Experimental Medicine and Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague, Czech Republic

2Institute of Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic 

Pages: 133 - 143 (PDF)

Corresponding author: Milan Jirsa, Institute for Clinical and Experimental Medicine (IKEM), Laboratory of Experimental Hepatology, Vídeňská 1958/9, 140 21 Prague 4, Czech Republic. E-mail: milan.jirsa@ikem.cz


Original Article

Differential Expression of Tripartite Motif-Containing Family in Normal Human Dermal Fibroblasts in Response to Porcine Endogenous Retrovirus Infection

(porcine endogenous retrovirus / tripartite motif-containing family / lipopolysaccharide /  xenotransplantation / oligonucleotide microarray)

M. W. KIMSA1, B. STRZALKA-MROZIK1, M. C. KIMSA2, U. MAZUREK1, C. KRUSZNIEWSKA-RAJS1, J. GOLA1, J. ADAMSKA1, M. TWARDOCH1 

1Department of Molecular Biology, 2Department of Food and Nutrition, Medical University of Silesia, Sosnowiec, Poland

Pages: 144 - 151 (PDF)

Corresponding author: Malgorzata W. Kimsa, Department of Molecular Biology, Medical University of Silesia, Jednosci 8, 41-200 Sosnowiec, Poland. Phone: (+48) 32 364 10 26; fax: (+48) 32 364 10 20; e-mail: gosiakimsa@gmail.com