Volume 62 (2016) No. 3

 

Original Article

Iron Overload Causes Alterations of E-Cadherin in the Liver

(iron overload / E-cadherin / liver / adherens junctions)

Y. FUJIKURA1,3, J. KRIJT1, C. POVÝŠIL2, Z. MĚLKOVÁ3, P. PŘIKRYL1, M. VOKURKA1, E. NEČAS1

1Institute of Pathophysiology, 2Institute of Pathology, 3Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University in Prague, Czech Republic

Pages: 95 - 102 (PDF)

Corresponding author: Yuzo Fujikura, Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University in Prague, Studničkova 7, 12800 Prague 2, Czech Republic Phone: (+420) 224 968 460; Fax: (+420) 224 968 588; e-mail: yuzofujikura@hotmail.com


Original Article

Generation of GFP Native Protein for Detection of Its Intracellular Uptake by Cell-Penetrating Peptides

(GFP / prokaryotic expression systems / cell-penetrating peptides / Pep-1 / CADY-2)

S. KADKHODAYAN1, S. M. SADAT2, S. IRANI1, F. FOTOUHI3, A. BOLHASSANI2

1Department of Biology, School of Basic Science, Science and Research Branch, Islamic Azad University, Tehran, Iran

2Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran

3Influenza Research Lab., Department of Virology, Pasteur Institute of Iran, Tehran, Iran

Pages: 103 - 109 (PDF)

Corresponding author: Azam Bolhassani, Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran. Phone: (+98) 2166953311 Ext. 2240; Fax: (+98) 21 66465132; e-mail: azam.bolhassani@yahoo.com


Original Article

Importance of Tumour Suppressor Gene Methylation in Sinonasal Carcinomas

(MS-MLPA / DNA methylation / sinonasal carcinoma / epigenetics / HPV)

M. CHMELAŘOVÁ1, I. SIRÁK2, M. MŽIK1, K. SIEGLOVÁ3, H. VOŠMIKOVÁ3, P. DUNDR4, K. NĚMEJCOVÁ4, J. MICHÁLEK5, M. VOŠMIK2, V. PALIČKA1, J. LACO3

1Institute for Clinical Biochemistry and Diagnostics, 2Department of Oncology and Radiotherapy, 3The Fingerland Department of Pathology, Charles University in Prague – Faculty of Medicine in Hradec Králové and University Hospital in Hradec Králové, Czech Republic

4Institute of Pathology, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic

5Department of Clinical and Molecular Pathology, Palacký University Olomouc, Faculty of Medicine and Dentistry and University Hospital Olomouc, Czech Republic

Pages: 110 - 119 (PDF)

Corresponding author: Marcela Chmelařová, Institute for Clinical Biochemistry and Diagnostics, University Hospital Hradec Králové, Sokolská 581, 500 05 Hradec Králové, Czech Republic. Phone: (+ 420) 495 833 864; e-mail: chmelarovamarcela@seznam.cz


Original Article

The Quality Control of Mesenchymal Stromal Cells by in Vitro Testing of Their Immunomodulatory Effect on Allogeneic Lymphocytes

(mesenchymal stromal cells / allogeneic / immunosuppression / GVHD)

D. LYSÁK1, L. KOUTOVÁ1, M. HOLUBOVÁ1, T. VLAS2, M. MIKLÍKOVÁ3, P. JINDRA4

1Department of Haematology and Oncology, and University Hospital in Pilsen, Pilsen, Czech Republic

2Institute of Immunology and Allergology, Charles University in Prague, Faculty of Medicine in Pilsen and University Hospital in Pilsen, Pilsen, Czech Republic

3Biomedical Centre, Charles University in Prague, Faculty of Medicine in Pilsen, Pilsen, Czech Republic

4Czech National Marrow Donor Registry (CS-2), Pilsen, Czech Republic

Pages: 120 - 130 (PDF)

Corresponding author: Daniel Lysák, Department of Haematology and Oncology, Charles University in Prague, Faculty of Medicine in Pilsen and University Hospital in Pilsen, Alej Svobody 80, 304 60 Pilsen, Czech Republic. Phone: (+420) 377 103 722; Fax: (+420) 377 104 628; e-mail: lysak@fnplzen.cz


Original Article

Down-regulation of AQP4 Inhibits Proliferation, Migration and Invasion of Human Breast Cancer Cells

(breast cancer / AQP4 / siRNA / E-cadherin / ERK pathway)

Y.-B. LI1, S.-R. SUN1, X.-H. HAN2

1Renmin Hospital of Wuhan University, Wuhan, China

2Inner Mongolia People’s Hospital, Hohhot, China

Pages: 131 - 137 (PDF)

Corresponding author: Sheng-Rong Sun, Renmin Hospital of Wuhan University, Wuhan 430060, China. E-mail: shukege@163.com