Volume 62 (2016) No. 4

 

 Original Article

Neurological Deficits of an Rps19(Arg67del) Model of Diamond-Blackfan Anaemia

(Diamond-Blackfan anaemia / RPS19 / transgenic mouse / gait / neuromuscular function / fear conditioning)

A. KUBIK-ZAHORODNA, B. SCHUSTER, I. KANCHEV, R. SEDLÁČEK

Laboratory of Transgenic Models of Diseases, Division BIOCEV, Institute of Molecular Genetics of the ASCR, v. v. i., Prague, Czech Republic

Pages: 139 - 147 (PDF)

Corresponding author: Radislav Sedláček, Agnieszka Kubik-Zahorodna, Laboratory of Transgenic Models of Diseases, BIOCEV Division, Institute of Molecular Genetics of the ASCR, v. v. i., Vídeňská 1083, 142 20 Prague 4, Czech Republic. Phone: (+420) 325 873 243 (R. S.); e-mails: radislav.sedlacek@img.cas.cz, agnieszka.kubik-zahorodna@img.cas.cz


 

 

Original Article

Changes in Liver Ganglioside Metabolism in Obstructive Cholestasis – the Role of Oxidative Stress

(cholestasis / gangliosides / haem oxygenase / liver)

V. ŠMÍD1,2, T. PETR1, K. VÁŇOVÁ1, J. JAŠPROVÁ1, J. ŠUK1, L. VÍTEK1,2, F. ŠMÍD1, L. MUCHOVÁ1

1Institute of Medical Biochemistry and Laboratory Diagnostics, 24th Department of Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic

Pages: 148 - 159 (PDF)

Corresponding author: Lucie Muchová, Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Kateřinská 32, 121 08 Prague 2, Czech Republic. Phone: (+420) 224 964 199; Fax: (+420) 224 962 532; e-mail: lucie.muchova@lf1.cuni.cz


 

Original Article

Mast Cells Might Have a Protective Role against the Development of Calcification and Hyalinisation in Severe Aortic Valve Stenosis

(mast cells / remodelling / inflammation / aortic valve stenosis)

A. MILUTINOVIC1, D. PETROVIČ1,2, M. ZORC1,2, O. VRASPIR PORENTA1, M. ARKO1, A. PLESKOVIČ3, A. ALIBEGOVIC4, R. ZORC-PLESKOVIC1

1University of Ljubljana, Faculty of Medicine, Institute of Histology and Embryology, Ljubljana, Slovenia

2 MC Medicor, Ljubljana, Slovenia

3University Medical Centre of Ljubljana, Department of Internal Medicine, Ljubljana, Slovenia

4University of Ljubljana, Faculty of Medicine, Institute of Forensic Medicine, Ljubljana, Slovenia

Pages: 160 - 166 (PDF)

Corresponding author: Aleksandra Milutinovic, University of Ljubljana, Faculty of Medicine, Institute of Histology and Embryology, Korytkova 2 1000 Ljubljana, Slovenia. Phone: (+386) 1 543 73 60; Fax: (+386) 1 543 73 61; e-mail: sandramilutinovic@yahoo.com


 

 

Original Article

Comparison of the Radiosensitizing Effect of ATR, ATM and DNA-PK Kinase Inhibitors on Cervical Carcinoma Cells

(γ radiation / HeLa cells / ATM / ATR and DNA PK inhibitors / VE-821)

J. VÁVROVÁ1, L. ZÁRYBNICKÁ1, P. JOŠT2, A. TICHÝ1, M. ŘEZÁČOVÁ3, Z. ŠINKOROVÁ1, J. PEJCHAL1

1Department of Radiobiology, 2Centre of Advanced Studies, Faculty of Military Health Sciences, Hradec Králové, University of Defence Brno, Czech Republic

3Institute of Medical Biochemistry, Charles University Prague, Faculty of Medicine in Hradec Králové, Czech Republic

Pages: 167 - 174 (PDF)

Corresponding author: Jiřina Vávrová, Department of Radiobiology, Faculty of Military Health Sciences, University of Defence, Třebešská 1575, 500 01 Hradec Králové, Czech Republic. Phone: (+420) 776 050 946; Fax: (+420) 495513018; e-mail: jirina.vavrova@unob.cz


Short Communication

Conditional Knockout of the MicroRNA 17-92 Cluster in Type-I Collagen-Expressing Cells Decreases Alveolar Bone

Size and Incisor Tooth Mechanical Properties

(alveolar bone / MiR17-92 cluster / incisors / lower jaw)

M. IBRAHIM, S. MOHAN, M. J. XING, C. KESAVAN

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA, USA

Pages: 175 - 179 (PDF)

Corresponding author:  Chandrasekhar Kesavan, Musculoskeletal Disease Center, Research Service, VA Loma Linda Healthcare System, 11201 Benton Street, Loma Linda, CA 92357, USA. Fax: (+01) 190 97961680; e-mail: Chandrasekhar.Kesavan@va.gov