Volume 63 (2017) No. 2
Review Article
Putative Effects of Sex Hormones on Urinary Tract Infection
(kidney disease / bacteriuria / bladder / oestrogen / testosterone / progesterone)
T. BRACHTLOVÁ, R. GARDLÍK, L. TÓTHOVÁ
Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia
Pages: 35 - 41 (PDF)
Corresponding author: Tereza Brachtlová, Institute of Molecular Biomedicine, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia. Phone: (+421) 904 404 174; e-mail: tereza.brachtl@gmail.com
Original Article
Moringa olifeira Lam. Stimulates Activation of the Insulin-Dependent Akt Pathway. Antidiabetic Effect in a Diet-Induced Obesity (DIO) Mouse Model
(Moringa olifeira / insulin resistance / hyperglycaemia / hyperinsulinaemia / DIO mice / Akt / GLut4 / SREBP-1 / PPARα)
E. S. ATTAKPA1, 3*, M. M. SANGARÉ1, G. J. BÉHANZIN1, J.-M. ATEGBO1, B. SERI2, N. A. KHAN3
1Laboratoire de Physiopathologie Moléculaire et Toxicologie, Département de Physiologie Animale, Faculté des Sciences et Techniques, Université d’Abomey Calavi Cotonou, Rép. du Bénin
2Laboratoire de Neurosciences, Unité de Formation Biosciences 22 BP 582 Abidjan 22, Université de Cocody-Abidjan, Rép. de Côte-d’Ivoire
3INSERM U866, Physiologie de la Nutrition & Toxicologie. Université de Bourgogne, Dijon, France
Pages: 42 - 51 (PDF)
Corresponding author: Eugène Sèlidji Attakpa, Laboratoire de Physiopathologie Moléculaire et Toxicologie, Département de Physiologie Animale, Faculté des Sciences et Techniques, Université d’Abomey Calavi Cotonou, Rép. du Bénin. Phone: (+229) 97-55-21-25; e-mail: eattakpa@yahoo.fr
Original Article
Downregulation of p68 RNA Helicase (DDX5) Activates a Survival Pathway Involving mTOR and MDM2 Signals
(p68 RNA helicase / mTOR / MDM2 / IRES / c-MYC)
M. KOKOLO, M. BACH-ELIAS
Institute of Biomedical Research of Barcelona – Spanish National Research Council (CSIC), Barcelona, Spain
Pages: 52 - 59 (PDF)
Corresponding author: Montse Bach-Elias, CSIC c/ Egipcíacas 15, 08001 Barcelona, Spain. E-mail: montse.bach@iibb.csic.es
Original Article
Novel Mutation (T273R) in Thyroid Hormone Receptor β Gene Provides Further Insight into Cryptic Negative Regulation by Thyroid Hormone
(thyroid hormone receptor β / negative regulation / negative feedback regulation / syndrome of resistance to thyroid hormone / RTH / T273R)
F. KAŠŠÁK1, V. HÁNA2, V. SAUDEK3, M. KOSTROUCHOVÁ1
1Biocev, First Faculty of Medicine, Charles University, Vestec, Czech Republic
23rd Medical Department, Department of Endocrinology and Metabolism, First Faculty of Medicine, Charles University, Prague, Czech Republic
3University of Cambridge Metabolic Research Laboratories, Wellcome Trust–Medical Research Council, Institute of Metabolic Science, Cambridge, United Kingdom
Pages: 60 - 66 (PDF)
Corresponding author: Filip Kaššák, BIOCEV, First Faculty of Medicine, Charles University, Průmyslová 595, 252 50 Vestec, Czech Republic. E-mail: filip.kassak@me.com
Original Article
Spontaneously Hypertensive Rat Chromosome 2 with Mutant Connexin 50 Triggers Divergent Effects on Metabolic Syndrome Components
(metabolic syndrome / connexin / animal models / congenic strain)
O. ŠEDA1, D. KŘENOVÁ1, L. ŠEDOVÁ1, L. KAZDOVÁ2, M. KRUPKOVÁ1, B. CHYLÍKOVÁ1, F. LIŠKA1, V. KŘEN1
1Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic
2Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
Pages: 67 - 77 (PDF)
Corresponding author: Ondřej Šeda, Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Albertov 4, 128 00 Prague 2, Czech Republic. Phone: (+420) 224 968 180; Fax (+420) 224 918 666; e-mail: oseda@lf1.cuni.cz
Original Article
Influence of Cytochrome P450, ABC and SLC Gene Polymorphisms on Imatinib Therapy Outcome of Patients with Gastrointestinal Stromal Tumours (GIST)
(gastrointestinal stromal tumours / KIT mutation / intestinal tumours / imatinib / pharmacogenetics / genetic polymorphisms)
K. WASIELEWSKI1, B. WASAG1,2, A. WOZNIAK3, J. PIKIEL4, A. KOWALIK5, C. OSUCH6, E. BYLINA7, J. A. SIEDLECKI8, P. RUTKOWSKI7, J. LIMON1,2
1Department of Biology and Medical Genetics, Medical University of Gdansk, Gdansk, Poland
2Laboratory of Clinical Genetics, University Clinical Centre, Gdansk, Poland
3Laboratory of Experimental Oncology, Department of Oncology, KU Leuven and Department of General Medical Oncology, University Hospitals in Leuven, Leuven, Belgium.
4Regional Oncology Centre, Gdansk, Poland
5Department of Molecular Diagnostics, Holycross Cancer Centre, Kielce, Poland
6Department of General Surgery, Medical Faculty, Jagiellonian University, Krakow, Poland
7Department of Soft Tissue/Bone Sarcoma and Melanoma, 8Department of Translational and Molecular Oncology, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland
Pages: 78 - 83 (PDF)
Corresponding author: Kacper Wasielewski, Department of Biology and Medical Genetics, Medical University of Gdansk, Dębinki 1, 80-211, Gdańsk, Poland. E-mail: k.wasielewski@gumed.edu.pl
