Volume 64 (2018) No. 1

Original Article

Valproic Acid Decreases the Nuclear Localization of MDT-28, the Nematode Orthologue of MED28

(Mediator complex / valproic acid / nuclear localization / MDT-28 / MED28)

M. KOSTROUCHOVÁ1,2,*, V. KOSTROUCHOVÁ1, P. YILMA1, A. BENDA3, V. MANDYS2, M. KOSTROUCHOVÁ1,‡

1Biocev, First Faculty of Medicine, Charles University, Prague, Czech Republic

2Department of Pathology, Third Faculty of Medicine, Charles University, Prague, Czech Republic

3Imaging Methods Core Facility, Biocev, Faculty of Science, Charles University, Prague, Czech Republic

Pages: 1 - 9 (PDF)

Corresponding author: Markéta Kostrouchová, Biocev, First Faculty of Medicine, Charles University, Prague, Průmyslová 595, 252 42 Vestec, Czech Republic. Phone: (+420) 325 873 017; e-mail: marketa.kostrouchova@lf1.cuni.cz


Original Article

Extracellular DNA as a Prognostic and Therapeutic Target in Mouse Colitis under DNase I Treatment

(DNase / DSS-induced colitis / extracellular DNA / inflammation / inflammatory bowel disease)

J. BÁBÍČKOVÁ1,2, J. ČONKA1, L. JANOVIČOVÁ1, M. BORIš3, B. KONEČNÁ1, R. GARDLÍK1

1Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava Slovakia

2Department of Clinical Medicine, University of Bergen, Bergen, Norway

3Institute of Electronics and Photonics, Faculty of Electrical Engineering and Information Technology,
Slovak University of Technology, Bratislava, Slovakia

Pages: 10 - 15 (PDF)

Corresponding author: Roman Gardlík, Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Sasinkova 4, Bratislava 811 08, Slovakia. Phone: (+421) 2 59357 296; Fax: (+421) 2 59357 631; e-mail: romangardlik@gmail.com


Original Article

Lactoferrin Prevents Susceptibility of WEHI 231 Cells to Anti-Ig-Induced Cell Death Promoting Cell Differentiation

(WEHI 231 cells / lactoferrin / apoptosis / signalling molecules / anti-mouse Ig antibodies)

E. ZACZYŃSKA1, I. KOCHANOWSKA1, M. KRUZEL2, M. ZIMECKI1

1Department of Experimental Therapy, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland

2McGovern Medical School, University of Texas, Health Science Center, Houston, Texas, USA

Pages: 16 - 22 (PDF)

Corresponding author: Michał Zimecki, The Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wroclaw, Poland. Phone: (+48) 713709953; Fax: (+48) 713372171; e-mail: zimecki@iitd.pan.wroc.pl


Original Article

Pyrogallol Induces Apoptosis in Human Platelets

(apoptosis / γ-glutamyl transpeptidase / glutathione / mitochondrial membrane potential / platelets / thrombocytopenia / pyrogallol / polyphenol)

G. BRUGES1, W. VENTURINI1, G. CRESPO1, M. LÓPEZ ZAMBRANO1,2

1Laboratorio de Hemostasia y Genética Vascular. Centro de Biofísica y Bioquímica. Instituto Venezolano de Investigaciones Científicas, Caracas, Venezuela

2Institute of Biochemistry, Medical School, Justus Liebig University, Giessen, Germany

Pages: 23 - 30 (PDF)

Corresponding author: Mercedes López Zambrano, Instituto Venezolano de Investigaciones Científicas. Centro de Biofísica y Bioquímica, Lab. de Hemostasia y Genética Vascular. Carretera Panamericana
Km 11. Caracas 1020A, Venezuela. Phone: (+58) 212-504-1903; Fax: (+58) 212-504-1093; e-mail: melopez73@hotmail.com


Short Communication

Buccal Respiratory Chain Complexes I and IV Quantities in Huntington’s Disease Patients

(Huntington’s disease / mitochondria / buccal epithelium / OXPHOS / dipstick immunoassay)

P. DUŠEK1, M. RODINOVÁ2, I. LIŠKOVÁ1, J. KLEMPÍŘ1,3, J. ZEMAN2, J. ROTH1, H. HANSÍKOVÁ2

1Department of Neurology and Centre of Clinical Neuroscience, 2Laboratory for the Study of Mitochondrial Disorders, Department of Paediatrics and Adolescent Medicine, 3Institute of Anatomy, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic

Pages: 31 - 34 (PDF)

Corresponding author: Hana Hansíková, Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Ke Karlovu
2, 128 08 Prague 2, Czech Republic. Phone: (+420) 224 967 748; e-mail: hana.hansikova@lf1.cuni.cz