Volume 64 (2018) No. 2

Review Article

Notch and Cdk5 in Zebrafish Mindbomb Mutant: Co-regulation or Coincidence?

(neuron / delta / Ubiquitin ligase / mindbomb / Cdk5 / Notch)

J. KANUNGO1, 3*, M. T. GOSWAMI2, H. C. PANT3

1Division of Neurotoxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA

2National Institute of Children’s Health and Development, 3National Institute of Neuronal Disorders and Stroke, National Institute of Health, Bethesda, MD, USA

Pages: 35 - 40 (PDF)

Corresponding author: Jyotshna Kanungo, Division of Neurotoxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA. Phone: (+001) 870-543-7591; Fax: (+001) 870-543-7143; e-mail: jyotshnabala.kanungo@fda.hhs.gov


Original Article

HPV Status and Mutation Analysis Using Multiparallel Sequencing in Distal Oesophageal and Gastro-oesophageal Junction Adenocarcinomas

(gastro-oesophageal junction cancer / oesophageal cancer / adenocarcinoma / multiparallel sequencing / gene mutation / human papillomavirus)

M. Vošmik1, H. Vošmiková2, K. Sieglová2, I. Sirák1, J. Laco2, A. Ryška2, J. Petera1, B. Melichar3, R. Soumarová4

1Department of Oncology and Radiotherapy, 2The Fingerland Department of Pathology, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králove, Hradec Králové, Czech Republic

3Department of Oncology, Palacký University, Faculty of Medicine and Dentistry and University Hospital Olomouc, Olomouc, Czech Republic

4Department of Radiotherapy and Oncology, Charles University, Third Faculty of Medicine and University

Hospital Královské Vinohrady, Prague, Czech Republic

Pages: 41 - 45 (PDF)

Corresponding author: Igor Sirák, Department of Oncology and Radiotherapy, University Hospital Hradec Králové, Sokolská 581, 500 05 Hradec Králové, Czech Republic. igor.sirak@fnhk. cz; Phone: (+420) 495 832 363; Fax: (+420) 495 832 081. e-mail: igor.sirak@fnhk.cz.


Original Article

ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans

(lifespan / lysosome-related organelle / methyltransferase / multifunctional enzyme / Nile red / oxidoreductase, RNA-binding / transferase)

J. KOLLÁROVÁ1, M. KOSTROUCHOVÁ1,2,#, A. BENDA3, M. KOSTROUCHOVÁ1*

1BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic

2Department of Pathology, Third Faculty of Medicine, Charles University, Prague, Czech Republic

3Imaging Methods Core Facility, BIOCEV, Faculty of Science, Charles University, Prague, Czech Republic

Pages: 46 - 58 (PDF)

Corresponding author: Marta Kostrouchová, BIOCEV, First Faculty of Medicine, Charles University, Průmyslová 595, 252 50 Vestec, Czech Republic. E-mail: marta.kostrouchova@lf1.cuni.cz


Original Article

Nos3 Gene Rs1799983 and Rs2070744 Polymorphisms in Patients with Periodontal Disease

(gene polymorphism / NOS3 gene / periodontal disease)

M. MAZUREK-MOCHOL1, M. KOZAK2, M. SAWCZUK3, A. MACIEJEWSKA3, D. MALINOWSKI4, K. SAFRANOW5, A. PAWLIK6

1Department of Periodontology, 2Department of Prosthetics, 4Department of Pharmacology, 5Department of Biochemistry and Medical Chemistry, 6Department of Physiology, Pomeranian Medical University, Szczecin, Poland

3Department Faculty of Physical Education and Health Promotion, University of Szczecin, Szczecin, Poland

Pages: 59 - 64 (PDF)

Corresponding author: Andrzej Pawlik, Department of Physiology, Pomeranian Medical University, Powstancow Wlkp. 72, 70-111 Szczecin, Poland. Phone: (+48) 914 661 611; Fax: (+48) 914 661 612; e-mail: pawand@poczta.onet.pl


Original Article

First Bosnian Study of the Relationship between APOE rs7412 and rs429358 Variants and Pregnancy Loss

(APOE gene variants / Bosnian women / miscarriage / real-time PCR)

G. ADLER1, E. MAHMUTBEGOVIC2, I. UZAR3, M. A. ADLER4, N. MAHMUTBEGOVIC5, A. VALJEVAC6

1Department of Studies in Antropogenetics and Biogerontology, 3Department of General Pharmacology and Pharmacoeconomics, Pomeranian Medical University, Szczecin, Poland

2Institution of Health Protection of Women and Motherhood Canton Sarajevo, Sarajevo, Bosnia and
Herzegovina

4Warsaw School of Economics, Warsaw, Poland

5Neurology Clinic, Clinical Center of University of Sarajevo, Sarajevo, Bosnia and Herzegovina

6Laboratory for Molecular Medicine, Center for Genetics, Medical Faculty, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Pages: 65 - 69 (PDF)

Corresponding author: Grażyna Adler, Department of Studies in Antropogenetics and Biogerontology, Pomeranian Medical University, Żołnierska 48, 71-210 Szczecin, Poland. Phone/Fax: (+48) 914 800 958; e-mail: gra2@op.pl