Volume 65 (2019) No. 4
Original Article
Polymorphisms rs2167444 and rs508384 in the SCD1 Gene Are Linked with High ApoB-48 Levels and Adverse Profile of Cardiometabolic Risk Factors
(apolipoprotein B-48 / cardiometabolic risk factors / metabolic syndrome components / small-dense LDL /
oxidative stress / fatty acid desaturases / SCD1 polymorphisms)
B. STAŇKOVÁ1, J. MACÁŠEK1, M. ZEMAN1, M. VECKA1, E. TVRZICKÁ1,
M. JÁCHYMOVÁ2, A. SLABÝ1, A. ŽÁK1
14th Department of Medicine, 2Institute of Clinical Chemistry and Laboratory Diagnostics, First Faculty
of Medicine, Charles University and General University Hospital, Prague, Czech Republic
Pages: 159 - 169 (PDF)
Corresponding author: Aleš Žák, 4th Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital, U Nemocnice 2, 128 08 Prague, Czech Republic; Phone: (+420) 224 962 091; e-mail: zak.ales@email.cz
Original Article
Role of the TAp63 Isoform in Recurrent Nasal Polyps
(nasal polyps / TAp6 / chronic rhinosinusitis)
A. TERRINONI1, R. PALOMBO1, C. PITOLLI1, S. CAPORALI5, R. DE BERARDINIS2,
S. CICCARONE2, A. LANZILLOTTA2, S. MAURAMATI3, G. PORTA4, M. MINIERI1,
G. MELINO1, S. BERNARDINI1, E. BRUNO2
1Department of Experimental Medicine, 2Department of Clinical Sciences and Translational Medicine, 5Department of Industrial Engineering, University of Rome Tor Vergata, Rome, Italy
3University of Pavia, Italy and Department of Otorhinolaryngology, University of Pavia, Foundation IRCCS Policlinico “San Matteo”, Pavia, Italy
4Department of Medicine and Surgery, University of Insubria, Varese, Italy
Pages: 170 - 180 (PDF)
Corresponding author: Ernesto Bruno, Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy. Phone/Fax: (+39) 06 2090 2340. Phone/Fax: (+39) 06 2090 2925, 06.2090.2930. E-mail: bruno.ernesto@libero.it.
Original Article
Stable COX17 Downregulation Leads to Alterations in Mitochondrial Ultrastructure, Decreased Copper Content and Impaired Cytochrome c Oxidase Biogenesis in HEK293 Cells
(Cox17 protein / copper chaperone / cytochrome c oxidase assembly / mitochondrial ultrastructure)
M. VANIŠOVÁ, D. BURSKÁ, J. KŘÍŽOVÁ, T. DAŇHELOVSKÁ, Ž. DOSOUDILOVÁ,
J. ZEMAN, L. STIBŮREK, H. HANSÍKOVÁ
Laboratory for Study of Mitochondrial Disorders, Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic
Pages: 181 - 187 (PDF)
Corresponding author: Hana Hansíková, Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Ke Karlovu 2, 128 08 Prague 2, Czech Republic. Phone: (+420) 224 967 748; e-mail: hana.hansikova@lf1.cuni.cz
Original Article
Strong Association between APOA5 Gene Polymorphisms and Hypertriglyceridaemic Episodes
(triglycerides / apoa5 / gene polymorphism / prediction)
M. VRABLIK1, J. A. HUBACEK2, D. DLOUHA2, M. SATNY1, V. ADAMKOVA3, R. CESKA1
13rd Department of Internal Medicine, Department of Endocrinology and Metabolism, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
2Centre for Experimental Medicine, 3Department of Preventive Cardiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
Pages: 188 - 194 (PDF)
Corresponding author: Michal Vrablík, 3rd Department of Internal Medicine, Department of Endocrinology and Metabolism, First Faculty of Medicine, Charles University and General University Hospital, U Nemocnice 1, 128 08 Prague 2, Czech Republic. Phone: (+420) 22496 2122; fax (+420) 22406 6677; e-mail: michal.vrablik@athero.cz
Original Article
Study of Aberrant Modifications in Peptides as a Test Bench to Investigate the Immunological Response to Non-Enzymatic Glycation
(protein glycation / immunological response / peptide / β-turn peptide structure / type 1 diabetes / SP-LISA)
F. NUTI1, A. GALLO2, F. REAL-FERNANDEZ1, C. RENTIER1,3, G. ROSSI4,5, F. PIARULLI2, P. TRALDI6, S. CARGANICO1,5, P. ROVERO4, A. LAPOLLA2*, A. M. PAPINI1,3*
1Laboratory of Peptide and Protein Chemistry and Biology, Department of Chemistry „Ugo Schiff“, University of Florence, Sesto Fiorentino, Italy
2Diabetology and Dietetics, Department of Medicine (DIMED), University of Padova, Padova, Italy
3PeptLab@UCP Platform and Laboratory of Chemical Biology EA4505, University Paris-Seine, Cergy-Pontoise CEDEX, France
4Laboratory of Peptide and Protein Chemistry and Biology, Department of NeuroFarBa, University of Florence, Sesto Fiorentino, Italy
5Pharma Quality Europe PQE SrL, Località Prulli, Firenze, Italy
6Istituto di Ricerca Pediatrica, Città della Speranza, Padova, Italy
Pages: 195 - 202 (PDF)
Corresponding author*: Anna Maria Papini, Laboratory of Peptide and Protein Chemistry and Biology – PeptLab, Department of Chemistry “Ugo Schiff”, University of Florence, Via della Lastruccia 13, I-50019 Sesto Fiorentino, Italy. Phone: (+39) 055 457 3561; e-mail: annamaria.papini@unifi.it – Annunziata Lapolla, Diabetology and Dietetics, Department of Medicine (DIMED), University of Padova, Padova, Italy. E-mail: annunziata.lapolla@unipd.it
