Volume 67 (2021) No. 1

Original Article

Questioning How to Define the “Ultra-High-Risk” Subgroup of Neuroblastoma Patients

(neuroblastoma / ultra-high risk / ALK expression)

A. B. Demir1,3, S. Aktas1, Z. Altun1, P. Ercetin1, T. C. AKTAS1, N. Olgun2

1Department of Basic Oncology, 2Department of Clinical Oncology, Institute of Oncology, Dokuz Eylul University, Izmir, Turkey

3Department of Basic Medical Sciences, Faculty of Medicine, Izmir University of Economics, Izmir, Turkey

Pages: 1 - 9 (PDF)

Corresponding author: Safiye Aktas, Dokuz Eylul University, Department of Basic Oncology, Institute of Oncology, 35330, Balcova, Izmir, Turkey. Phone: (+90) 232-4125891; e-mail: safiye.aktas@deu.edu.tr


Original Article

The Effects of Different Storage Conditions and Repeated Freeze/Thaw Cycles on the Concentration, Purity and Integrity of Genomic DNA

(gDNA / storage / freeze / thaw cycles / concentration / purity / integrity)

M. SAFARIKOVA1, A. A. KUBENA1, V. FRANKOVA2, T. ZIMA1, M. KALOUSOVA1

1Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic

2Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic

Pages: 10 - 15 (PDF)

Corresponding author: Marta Kalousova, Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital, Kateřinská 32, 121 08 Prague 2, Czech Republic, E-mail: marta.kalousova@lf1.cuni.cz


Original Article

T-Cell Activation: Post-Infection Diagnostic Tool for COVID-19

(COVID-19 / SARS-CoV-2 / T-cell activation)

P. SIMARA1,2, L. TESAROVA1,2, I. TAPUCHOVA1,2, J. CELEROVA1, I. KOUTNA1,2

1International Clinical Research Center of St. Anne’s University Hospital in Brno, Brno, Czech Republic

2Department of Histology and Embryology, Faculty of Medicine, Masaryk University, Brno, Czech Republic

Pages: 16 - 27 (PDF)

Corresponding author: Irena Koutná, International Clinical Research Center of St. Anne’s University Hospital in Brno, Pekařská 53, 656 91 Brno, Czech Republic. Phone: (+420) 543 187 751; e-mail: qkoutna@gmail.com


Original Article

Serum Cytokine Analysis Reveals Predictors of Progression from Chronic Hepatitis B to Liver Cirrhosis

(chronic hepatitis B / liver cirrhosis / cytokine profiling / IL-9 / GM-CSF / Il-2Rα)

F. CAI1,2, Y. ZHAO2, Q. CHEN1, Y. HU2, S. SU1, Y. LU1

1Research Center for Traditional Chinese Medicine Complexity System, Shanghai University of Traditional Chinese Medicine, Shanghai, China

2Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China

Pages: 28 - 36 (PDF)

Corresponding author: Shibing Su and Yiyu Lu, Research Center for Traditional Chinese Medicine Complexity System, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. E-mails: Shibingsu07@163.com and ava0048@163.com


Original Article

Investigation of the Inhibitory Effect of Platycodin D in Human Transitional Cell Carcinoma Cell Line 5637

(platycodin D / transitional cell carcinoma / proliferation / anti-tumour / migration)

X. G. LI1, S. GAO2, W .S. YANG2, S. SUN2

1Department of Urinary Surgery, Yanbian University Affiliated Hospital, Yanji, Jilin, China

2Department of Pathology, College of Medicine, Yanbian University, Yanji, Jilin, China

Pages: 37 - 47 (PDF)

Corresponding author: Shu Sun, Department of Pathology, College of Medicine, Yanbian University, Yanji, Jilin, China, 133002. Phone: (+86) 0433-243-5108; e-mail: sunshu@ybu.edu.cn