Volume 68 (2022) No. 5-6

Review Article

Genetics of T2DM and Its Chronic Complications: Are We Any Closer to the Individual Prediction of Genetic Risk?

(diabetes mellitus / diabetes complication / polymorphism / Central European population / genetic / GWAS / diabetic neuropathy / diabetic kidney disease / diabetic retinopathy / cardiovascular disease)

D. GALUŠKA1, L. DLOUHÁ2, J. A. HUBÁČEK3,4, K. KAŇKOVÁ1

1Department of Pathophysiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic

2Department of Anthropology and Human Genetics, Faculty of Science, Charles University, Prague, Czech Republic

3Experimental Medicine Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

43rd Department of Medicine – Department of Endocrinology and Metabolism, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic

Pages: 159-179 (PDF)

Corresponding author: Lucie Dlouhá, Department of Anthropology and Human Genetics, Faculty of Science, Charles University, Albertov 6, 128 00 Prague 2, Czech Republic. Phone: +420 736 436 491; e-mail: slukov.a@seznam.cz


Original Article

Up-regulation of MiR-146b-5p Inhibits Fibrotic Lung Pericytes via Inactivation of the Notch1/PDGFRβ/ROCK1 Pathway

(lung fibrosis / miR-146b-5p / Notch1/PDGFRβ/ROCK1 / extracellular matrix / bleomycin)

W. SHUAI1, Q. CHEN2, X. ZHOU1

1Departments of Critical Care Medicine, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha 410005, Hunan, China

2Department of Nephrology, Shanghai General Hospital, Shanghai 200000, China

Pages: 180-188 (PDF)

Corresponding author: Xu Zhou, Departments of Critical Care Medicine, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), Jiefang West Road, No. 61, Changsha 410005, Hunan, China. Phone: (+86) 139 0731 9339; e-mail: zhouxu66882022@163.com


Original Article

Mechanistic Study of Macranthoside B Effects on Apoptotic Cell Death in Human Cervical Adenocarcinoma Cells

(macranthoside B / oxidative stress / Akt/PDK1 / antioxidant enzymes / apoptosis)

Y. LI1, M. LI2,3, K. AHMED4, J. YANG1, L. SONG1, Z. G. CUI3, Y. HIRAKU3

1School of Life Science and Technology, Henan Institute of Science and Technology, Xinxiang, China

2School of Medicine, Xizang Minzu University, Weicheng District, Xianyang, Shaanxi, China

3Department of Environmental Health, University of Fukui School of Medical Sciences, Fukui, Japan

4Faculty of Eastern Medicine, Hamdard University, Islamabad, Pakistan

Pages: 189-200 (PDF)

Corresponding author: Zheng-Guo Cui, Department of Environmental Health, University of Fukui School of Medical Sciences, 23-3, Matsuokashimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui, 910-1193, Japan. Phone: +81 776 61 8337; Fax: +81 776 61 8107; e-mail: sai@u-fukui.ac.jp. Yusuke Hiraku, Department of Environmental Health, University of Fukui School of Medical Sciences, 23-3, Matsuokashimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui, 910-1193, Japan. Phone: +81 776 61 8335; Fax: +81 776 61 8107; e-mail: y-hiraku@u-fukui.ac.jp


Technical Notes

No Inhibitory Effect of Heparinized Blood on Real-Time PCR Analysis of Thrombophilic Mutations

(real-time PCR / anticoagulants / whole blood / thrombophilic mutations / inhibition / cycle threshold)

M. BERÁNEK1,2, J. HEGEROVÁ1, M. MICHAJLÍKOVÁ1, P. DULÍČEK3, V. PALIČKA1

1Institute of Clinical Biochemistry and Diagnostics, Faculty of Medicine in Hradec Králové, Charles University and University Hospital Hradec Králové, Czech Republic

2Department of Preventive Medicine, Faculty of Medicine in Hradec Králové, Charles University, Czech Republic

34th Department of Internal Medicine, Faculty of Medicine in Hradec Králové, Charles University and University Hospital Hradec Králové, Czech Republic

Pages: 201-205 (PDF)

Corresponding author: Martin Beránek, Institute of Clinical Biochemistry and Diagnostics, Faculty of Medicine in Hradec Králové, Charles University and University Hospital Hradec Králové, Sokolská 581, 500 05 Hradec Králové, Czech Republic. Phone: +420 49 583 3040; Fax: +420 49 583 2003; e-mail: beranek@lfhk.cuni.cz


Erratum

Chondrosarcoma with Target-Like Chondrocytes: Update on Molecular Profiling and Specific Morphological Features

C. POVÝŠIL, J. HOJNÝ, M. KAŇA

The original article was published in Folia Biologica (Praha) Volume 68, No. 3 (2022), 112-124.

Pages: 211 (PDF)